Column of Hope

Chiari and Syringomyelia Research Foundation - Working toward a life without pain.

Our Mission: Searching for better understanding, treatments, and cures for Chiari malformation, syringomyelia, neuropathic pain, spinal cord injury and related conditions.

Research Update - May 2018

Column of Hope (COH) is proud to announce its latest study published in the peer reviewed journal, Fluids and Barriers of the CNS, published April 29, 2018. This study documents our researchers’ work on findings regarding the role of perivascular and paravascular pathways in cerebral spinal fluid (CSF) flowing out of the spinal cord. This is another important building block in our understanding how to induce more CSF flow out of a syrinx thus reducing syrinx size.

In the past our syringomyelia (SM) research has made unprecedented... Read More



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A normal brain and spinal cord.
Chiari malformation and Syringomyelia.

What is Chiari Malformation?

Chiari I malformation is when the back of the skull is abnormally small. When this happens there is not enough room for the brain to fit in the skull properly and part of the brain is forced out of the skull into the spinal cord. Learn more

What is Syringomyelia?

Syringomyelia is a neurological disorder in which a cyst or cavity forms in the spinal cord. The cyst is called a syrinx and can expand and elongate over time, destroying the spinal cord. Learn more

What is Neuropathic Pain?

Neuropathic pain occurs when there is a malfunction in the part of the nervous system that tells the brain that tissue is injured. While there may be no injury to the tissue where the pain exists, the nervous system tells the brain that there is damage, causing pain. Learn more

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