Column of Hope

Chiari and Syringomyelia Research Foundation - Working toward a life without pain.

Our Mission: Searching for better understanding, treatments, and cures for Chiari malformation, syringomyelia, neuropathic pain, spinal cord injury and related conditions.

Research Update - April 29, 2022

We are pleased to announce Column of Hope’s latest published research, “Statistical shape models of the posterior cranial fossa and hindbrain volumes may provide a more robust clinical metric for Chiari malformation.” This is important follow-on work to the groundbreaking Column of Hope funded research, “Mechanisms of cerebellar tonsil herniation in patients with Chiari malformations as guide to clinical management,” from 2010. https://www.sciencedirect.com/science/article/abs/pii/S0021929022001476



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A normal brain and spinal cord.
Chiari malformation and Syringomyelia.

What is Chiari Malformation?

Chiari I malformation is when the back of the skull is abnormally small. When this happens there is not enough room for the brain to fit in the skull properly and part of the brain is forced out of the skull into the spinal cord. Learn more

What is Syringomyelia?

Syringomyelia is a neurological disorder in which a cyst or cavity forms in the spinal cord. The cyst is called a syrinx and can expand and elongate over time, destroying the spinal cord. Learn more

What is Neuropathic Pain?

Neuropathic pain occurs when there is a malfunction in the part of the nervous system that tells the brain that tissue is injured. While there may be no injury to the tissue where the pain exists, the nervous system tells the brain that there is damage, causing pain. Learn more

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